Symbol Name ID |
Gnrhr
gonadotropin releasing hormone receptor MGI:95790 |
* | Aspects of the system are reported to show a normal phenotype. |
Darker colors indicate more annotations |
Human Phenotypes | Hypogonadotropic hypogonadism |
Micropenis |
Decreased testicular size |
Cryptorchidism |
Primary amenorrhea |
Infertility |
Disease(s) Associated with GNRHR | ||||||
hypogonadotropic hypogonadism 7 with or without anosmia |
Mouse Phenotypes | reproductive system phenotype |
abnormal spermatocyte morphology |
arrest of male meiosis |
abnormal anogenital distance |
small male preputial gland |
small seminal vesicle |
abnormal ovary morphology |
absent corpus luteum |
decreased corpora lutea number |
absent tertiary ovarian follicles |
increased tertiary ovarian follicle number |
increased atretic ovarian follicle number |
impaired ovarian folliculogenesis |
decreased ovary weight |
small ovary |
abnormal testis morphology |
abnormal seminiferous tubule morphology |
small seminiferous tubules |
abnormal Leydig cell morphology |
decreased testis weight |
small testis |
cryptorchism |
small penis |
abnormal reproductive system morphology |
abnormal female reproductive system morphology |
abnormal internal female genitalia morphology |
thin uterus |
uterus hypoplasia |
constricted vagina orifice |
arrest of spermatogenesis |
abnormal male reproductive system morphology |
abnormal external male genitalia morphology |
abnormal internal male genitalia morphology |
small epididymis |
small gonad |
delayed vaginal opening |
abnormal reproductive system physiology |
abnormal female reproductive system physiology |
abnormal estrous cycle |
prolonged estrus |
prolonged metestrus |
absent estrous cycle |
prolonged estrous cycle |
female infertility |
reduced female fertility |
male infertility |
|
Availability | Mouse Genotype | ||||||||||||||||||||||||||||||||||||||||||||||
GnrhrGt(181A6)Cmhd/GnrhrGt(181A6)Cmhd | |||||||||||||||||||||||||||||||||||||||||||||||
Gnrhrhh/Gnrhrhh | |||||||||||||||||||||||||||||||||||||||||||||||
Gnrhrtm1(GNRHR1)Xen/Gnrhrtm1(GNRHR1)Xen | * | ||||||||||||||||||||||||||||||||||||||||||||||
Gnrhrtm1.1Bhr/Gnrhrtm1.1Bhr | * |
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 04/30/2024 MGI 6.23 |
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