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Symbol
Name
ID
Gnrhr
gonadotropin releasing hormone receptor
MGI:95790
Phenotype annotations related to reproductive system
*Aspects of the system are reported to show a normal phenotype.
Darker colors indicate more annotations
Human Phenotypes
Hypogonadotropic hypogonadism
Micropenis
Decreased testicular size
Cryptorchidism
Primary amenorrhea
Infertility
Disease(s) Associated with GNRHR
hypogonadotropic hypogonadism 7 with or without anosmia

Mouse Phenotypes
reproductive system phenotype
abnormal spermatocyte morphology
arrest of male meiosis
abnormal anogenital distance
small male preputial gland
small seminal vesicle
abnormal ovary morphology
absent corpus luteum
decreased corpora lutea number
absent tertiary ovarian follicles
increased tertiary ovarian follicle number
increased atretic ovarian follicle number
impaired ovarian folliculogenesis
decreased ovary weight
small ovary
abnormal testis morphology
abnormal seminiferous tubule morphology
small seminiferous tubules
abnormal Leydig cell morphology
decreased testis weight
small testis
cryptorchism
small penis
abnormal reproductive system morphology
abnormal female reproductive system morphology
abnormal internal female genitalia morphology
thin uterus
uterus hypoplasia
constricted vagina orifice
arrest of spermatogenesis
abnormal male reproductive system morphology
abnormal external male genitalia morphology
abnormal internal male genitalia morphology
small epididymis
small gonad
delayed vaginal opening
abnormal reproductive system physiology
abnormal female reproductive system physiology
abnormal estrous cycle
prolonged estrus
prolonged metestrus
absent estrous cycle
prolonged estrous cycle
female infertility
reduced female fertility
male infertility
Availability Mouse Genotype
GnrhrGt(181A6)Cmhd/GnrhrGt(181A6)Cmhd
Gnrhrhh/Gnrhrhh
Gnrhrtm1(GNRHR1)Xen/Gnrhrtm1(GNRHR1)Xen *
Gnrhrtm1.1Bhr/Gnrhrtm1.1Bhr *

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/30/2024
MGI 6.23
The Jackson Laboratory